The cancer epigenome--components and functional correlates
نویسندگان
چکیده
منابع مشابه
Targeting the epigenome with bioactive food components for cancer prevention.
Epigenetic processes participate in cancer development and likely influence cancer prevention. Global DNA hypomethylation, gene promoter hypermethylation and aberrant histone post-translational modifications are hallmarks of neoplastic cells which have been associated with genomic instability and altered gene expression. Because epigenetic deregulation occurs early in carcinogenesis and is pote...
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ژورنال
عنوان ژورنال: Genes & Development
سال: 2006
ISSN: 0890-9369
DOI: 10.1101/gad.1464906